DUNS Number - 67-716-4521  |  NCAGE CODE – 2444Y  |  FDA - FEI – 3014694901


Pharma / Bio Pharma

Crop Care






JRF offers a wide range of reproductive developmental and teratological studies, including maternal and foetal toxicity conducted in compliance with OECD, ICH and comparable guidelines as well as the GLP principles.

Evaluation of test substance toxicity to young and matured rodents and dogs proves safety to a certain level. However safety to the pregnant rodent females, their offspring, and their subsequent reproductive capability has become very important after the infamous anti emetic drug of the sixties.

In addition, we evaluate sperm motility, epididymal sperm reserves, homogenisation resistant sperm head counts and sperm morphology to access abnormalities, which forms an integral part in two generation toxicity studies


Type of Study:

  • Embryo-fetal
  • Reproduction and development toxicity study
  • Fertility study
  • Generation study

Guidelines: OECD, OPPTS/OCSPP, EU, JAPAN or specific requirement of study design.


Species: Rat, Mice and Rabbit


Route of administration: Oral (gavage, dietary and drinking water), Intravenous, Intramuscular, Subcutaneous.


Toxicokinetics: Plasma/Serum samples, Fetus/Pup blood.


Parameters generally performed in adult as well as pups:

  • Soft tissue examination
  • Cephalic evaluation
  • Skeletal evaluation with Single or Double staining
  • Neurobehavioural observation
  • Physical developmental landmark
  • Functional observation battery
  • Learning and memory
  • Auditory startle test
  • Histopathology
  • Estrous cycle evaluation and
  • Sperm analysis 

Surgical procedure: Ovariectomy and Castration.

Services available at following locations: