DUNS Number - 67-716-4521  |  NCAGE CODE – 2444Y  |  FDA - FEI – 3014694901


Pharma / Bio Pharma

Crop Care






JRF Global has over three decades of expertise and experience in genotoxicity, well honed by several global scientists of repute.

Genotox tests help identify pharmaceutical compounds which cause mutagenesis in living organisms, including man. These drugs are likely to affect the incidence of heritable disease in man and/or be potentially carcinogenic. Various tests based on diversified mutagenic effects have been recommended by ICH, for evaluation of mutagenic potential of various pharmaceutical products.

JRF has a well organized, purpose-built facility to conduct all the standard in vivo and in vitro genetic toxicology assays. Each assay uses protocols that comply with harmonized international guidelines.

Our dedicated team of scientists has vast experience in all aspects of genetic toxicology to evaluate each and every kind of pharmaceutical product. The results of these tests also provide an insight into the interpretation of carcinogenecity studies as well. 

In Vitro
Bacterial Reverse Mutation Test (Ames test) using Salmonella typhimurium and E. coli WP2 uvrA

Mini Ames Test
In Vitro Mammalian Chromosome Aberration Test using Chinese Hamster Ovary - K1 cell line
In Vitro Mammalian Chromosome Aberration Test using Human Peripheral Blood Lymphocytes
In Vitro Mammalian Cell Gene Mutation Test (HPRT assay) using Chinese Hamster Ovary-K1 cell line
In Vitro micronucleus test using Human Lymphocytes from Healthy Donor
In Vitro micronucleus test using CHO-K1 cell line
In Vitro Dermal Absorption using Human and Rat skin

In Vivo
In Vivo Mammalian Erythrocyte Micronucleus Test in Mice/Rat (With and without toxicokinetic)
In Vivo Mammalian Bone Marrow Chromosome Aberration Test in Mice/Rat (With and without

Services available at following locations: